Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060325 | 0.82 | ALDH1A1 (0.37) | ALDH1A1USP2LMNAALOX12MMP1 | |
| SCHEMBL17214454 | 0.82 | ALDH1A1 (0.37) | ALDH1A1USP2LMNAALOX12MMP1 | |
| SCHEMBL13563361 | 0.82 | CYP1A2 (0.45) | ALDH1A1LMNAMGLLPHGDHHTT | |
| SCHEMBL13563409 | 0.80 | CHRNB2 (0.38) | — | |
| SCHEMBL21320559 | 0.79 | — | — | |
| SCHEMBL13678355 | 0.72 | ALDH1A1 (0.34) | ALDH1A1USP2LMNAALOX12HPGD | |
| SCHEMBL24202216 | 0.72 | F2 (0.35) | ALDH1A1USP2LMNAALOX12HPGD | |
| SCHEMBL9112178 | 0.70 | ALDH1A1 (0.38) | ALDH1A1USP2LMNAALOX12MMP1 | |
| SCHEMBL9112173 | 0.70 | ALDH1A1 (0.38) | ALDH1A1USP2LMNAALOX12MMP1 | |
| SCHEMBL8243212 | 0.70 | ALDH1A1 (0.38) | ALDH1A1USP2LMNAALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020017587-A1 | PYRIDAZINONE DERIVATIVE | 大日本住友製薬株式会社 | 2020-01-23 | — | — | WO | disclosed |