Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647133 | 1.00 | MAPT (0.68) | MAPTMAPK1ARMAOBTYR | |
| SCHEMBL17459350 | 0.90 | MAPT (0.71) | MAPTMAPK1ARMAOBCYP1B1 | |
| SCHEMBL21647126 | 0.88 | TYR (0.72) | MAPTMAPK1ARMAOBTYR | |
| SCHEMBL21647110 | 0.88 | TYR (0.72) | MAPTMAPK1ARMAOBTYR | |
| SCHEMBL29837044 | 0.88 | TYR (0.72) | MAPTMAPK1ARMAOBTYR | |
| SCHEMBL1659465 | 0.84 | TYR (0.77) | MAPTMAOBTYRCYP1B1MEN1 | |
| SCHEMBL1659468 | 0.84 | TYR (0.77) | MAPTMAOBTYRCYP1B1MEN1 | |
| SCHEMBL27737862 | 0.83 | MAPT (0.57) | MAPTMAPK1ARMAOBTYR | |
| SCHEMBL27737861 | 0.83 | MAPT (0.57) | MAPTMAPK1ARMAOBTYR | |
| SCHEMBL10341663 | 0.83 | TYR (0.60) | MAPTMAPK1MAOBTYRCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890975-B | Compound with fused ring chroman structure and preparation method thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | claimed |
| CN-114890975-A | Compound with parachroman structure and preparation method thereof | 合肥工业大学 | 2022-08-12 | — | — | CN | claimed |
| CN-118852084-A | Method for promoting synthesis of selenoflavone by using visible light | 南通大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-116162079-B | Synthesis method of aminocoumarin compound | 浙江工业大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-116836198-A | Synthesis method of 2-aryl-4-phosphono-4H-chromene compound | 成都大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-114890975-B | Compound with fused ring chroman structure and preparation method thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-116162079-A | Synthesis method of aminocoumarin compound | 浙江工业大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-114890975-A | Compound with parachroman structure and preparation method thereof | 合肥工业大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-108774207-B | Cyclopenta [ c ] chromene compounds and process for preparing the same | 苏州大学张家港工业技术研究院 | 2021-12-17 | — | — | CN | disclosed |
| WO-2020024099-A1 | CYCLOPENTADIENYL [C] CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | 苏州大学张家港工业技术研究院 | 2020-02-06 | — | — | WO | disclosed |