Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647133 | 0.90 | MAPT (0.68) | MAPTMAPK1CXCL12DHODHGABRA3 | |
| SCHEMBL21647132 | 0.90 | MAPT (0.68) | MAPTMAPK1CXCL12DHODHGABRA3 | |
| SCHEMBL29837067 | 0.83 | MAPT (1.00) | MAPTMAPK1CXCL12ARMAOB | |
| SCHEMBL17459328 | 0.83 | MAPT (1.00) | MAPTMAPK1CXCL12ARMAOB | |
| SCHEMBL21647111 | 0.83 | MAPT (1.00) | MAPTMAPK1CXCL12ARMAOB | |
| SCHEMBL1225557 | 0.81 | LMNA (0.65) | MAPTMAPK1CXCL12MAOBCYP1B1 | |
| SCHEMBL1225556 | 0.81 | LMNA (0.65) | MAPTMAPK1CXCL12MAOBCYP1B1 | |
| SCHEMBL30383707 | 0.81 | MAPT (0.59) | MAPTMAPK1CXCL12DHODHMAOB | |
| SCHEMBL1225024 | 0.81 | MAPT (0.59) | MAPTMAPK1CXCL12DHODHMAOB | |
| SCHEMBL1225026 | 0.81 | MAPT (0.59) | MAPTMAPK1CXCL12DHODHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |