Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | USP8 | P40818 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647164 | 0.92 | TERT (0.57) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL22772252 | 0.90 | TERT (0.42) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL21647138 | 0.84 | TERT (0.57) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL21647151 | 0.84 | TERT (0.57) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL21668591 | 0.83 | CDK2 (0.40) | TERTKDM4EMAPTRECQL | |
| SCHEMBL22789421 | 0.82 | TERT (0.66) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL21647173 | 0.82 | TERT (0.66) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL21647175 | 0.80 | TERT (0.60) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL21668613 | 0.80 | TERT (0.63) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL22772266 | 0.79 | TERT (0.62) | TERTKDM4EALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020024977-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | 陕西麦科奥特科技有限公司 | 2020-02-06 | — | — | WO | disclosed |