Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22789466 | 0.91 | APP (0.39) | CDK2APPTERTATP1A1ATP1B1 | |
| SCHEMBL23473363 | 0.89 | CDK2 (0.38) | CDK2APPABCG2KDM4ECDK1 | |
| SCHEMBL21647177 | 0.83 | TERT (0.55) | TERTKDM4EMAPTRECQL | |
| SCHEMBL21668590 | 0.81 | CDK2 (0.54) | CDK2APPTERTATP1A1ATP1B1 | |
| SCHEMBL22772252 | 0.81 | TERT (0.42) | TERTKDM4EMAPTRECQL | |
| SCHEMBL21647164 | 0.74 | TERT (0.57) | TERTKDM4EMAPTRECQL | |
| SCHEMBL21647159 | 0.73 | APP (0.42) | CDK2APPTERTATP1A1ATP1B1 | |
| SCHEMBL22789251 | 0.72 | TERT (0.44) | CDK2APPTERTATP1A1ATP1B1 | |
| SCHEMBL21647180 | 0.72 | TERT (0.62) | CDK2APPTERTATP1A1ATP1B1 | |
| SCHEMBL4909482 | 0.72 | FBP1 (0.61) | CDK2APPTERTATP1A1ATP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020024977-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | 陕西麦科奥特科技有限公司 | 2020-02-06 | — | — | WO | disclosed |