Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 4/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12023184 | 0.84 | IDO1 (0.48) | SMN1; SMN2IDO1MAOAMAOBALOX15 | |
| SCHEMBL17506374 | 0.81 | AOC1 (0.52) | SMN1; SMN2EP300KAT2BKAT8MAOA | |
| SCHEMBL15784149 | 0.78 | KDM4E (0.38) | IDO1EP300KAT2BKAT8MAOA | |
| SCHEMBL6635250 | 0.77 | LIMK1 (0.56) | SMN1; SMN2MAOAMAOBTSHRALDH1A1 | |
| SCHEMBL29939393 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL13149262 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL4434876 | 0.77 | GPBAR1 (0.43) | SMN1; SMN2MAOAMAOBTSHRALDH1A1 | |
| SCHEMBL3954650 | 0.77 | GSK3B (0.45) | SMN1; SMN2IDO1MAOAMAOBALOX15 | |
| SCHEMBL2068581 | 0.77 | ALDH1A1 (0.68) | SMARCA2SMARCA4NR1I2PBRM1BRD4 | |
| SCHEMBL31359603 | 0.76 | ALDH1A1 (0.57) | SMARCA2SMARCA4NR1I2PBRM1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210347785-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) | 2021-11-11 | — | — | US | disclosed |
| EP-3831823-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020025030-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | 上海轶诺药业有限公司 | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347785-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | CD274, PDCD1, PDCD1LG2 | SMARCA2 1617/4885SMARCA4 1391/4885NR1I2 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.