Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 6/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31548955 | 1.00 | FABP1 (0.56) | FABP1HTR6FABP4LTB4RLTB4R2 | |
| SCHEMBL31549014 | 0.95 | HTR6 (0.56) | FABP1HTR6FABP4LTB4RLTB4R2 | |
| SCHEMBL21647681 | 0.95 | HTR6 (0.56) | FABP1HTR6FABP4LTB4RLTB4R2 | |
| SCHEMBL21669425 | 0.94 | FABP1 (0.56) | FABP1HTR6FABP4LTB4RLTB4R2 | |
| SCHEMBL31548996 | 0.90 | HTR6 (0.57) | FABP1HTR6FABP4LTB4RHDAC1 | |
| SCHEMBL21647706 | 0.90 | HTR6 (0.57) | FABP1HTR6FABP4LTB4RHDAC1 | |
| SCHEMBL31548985 | 0.87 | FABP1 (0.67) | FABP1HTR6FABP4HDAC1HDAC8 | |
| SCHEMBL21647848 | 0.87 | FABP1 (0.67) | FABP1HTR6FABP4HDAC1HDAC8 | |
| SCHEMBL21647823 | 0.86 | HTR6 (0.50) | FABP1HTR6FABP4LTB4RLTB4R2 | |
| SCHEMBL31549008 | 0.86 | HTR6 (0.50) | FABP1HTR6FABP4LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089532-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-24 | — | — | US | disclosed |
| US-11261154-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-01 | — | — | US | disclosed |
| US-20210332009-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | US | disclosed |
| EP-3831810-A1 | BENZENE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261154-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | FABP1 2477/4885HTR6 3842/4885FABP4 882/4885 |
| US-20210332009-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | FABP1 2477/4885HTR6 3842/4885FABP4 882/4885 |
| US-20220089532-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | FABP1 2477/4885HTR6 3842/4885FABP4 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.