Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440797 | 1.00 | AKR1B1 (0.53) | AKR1B1ADRB3ADRB2EPHX1CYP1A2 | |
| SCHEMBL22161006 | 0.84 | AKR1B1 (0.55) | AKR1B1ADRB3ADRB2CYP1A2LMNA | |
| SCHEMBL23680088 | 0.84 | AKR1B1 (0.54) | AKR1B1ADRB3ADRB2CYP1A2LMNA | |
| SCHEMBL11143478 | 0.83 | EPHX1 (0.51) | AKR1B1EPHX1CYP1A2CPA1CPB1 | |
| Hydrochloric Acid SCHEMBL9778060 | 0.83 | PNMT (0.47) | AKR1B1ADRB3ADRB2CYP1A2ADRB1 | |
| SCHEMBL3929106 | 0.81 | AKR1B1 (0.55) | AKR1B1ADRB3ADRB2CYP1A2LMNA | |
| SCHEMBL28263669 | 0.80 | AKR1B1 (0.54) | AKR1B1ADRB3ADRB2CYP1A2LMNA | |
| SCHEMBL30408970 | 0.79 | SLC7A5 (0.45) | ADRB3ADRB2ADRB1TSHRSLC7A5 | |
| SCHEMBL29483752 | 0.79 | SLC7A5 (0.45) | ADRB3ADRB2ADRB1TSHRSLC7A5 | |
| SCHEMBL28608667 | 0.79 | SLC7A5 (0.45) | ADRB3ADRB2ADRB1TSHRSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089532-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-24 | — | — | US | disclosed |
| US-11261154-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-01 | — | — | US | disclosed |
| US-20210332009-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | US | disclosed |
| EP-3831810-A1 | BENZENE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261154-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | AKR1B1 2227/4885ADRB3 1124/4885ADRB2 832/4885 |
| US-20210332009-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | AKR1B1 2227/4885ADRB3 1124/4885ADRB2 832/4885 |
| US-20220089532-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | AKR1B1 2227/4885ADRB3 1124/4885ADRB2 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.