Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29692391 | 0.99 | BCHE (0.41) | BCHEBACE1HTR1ACHRM2SCN8A | |
| SCHEMBL21648451 | 0.94 | BCHE (0.38) | BCHEBACE1HTR1ACHRM2SCN8A | |
| SCHEMBL21648351 | 0.90 | BCHE (0.41) | BCHEBACE1HTR1ACHRM2SCN8A | |
| Hydrochloric Acid SCHEMBL29692416 | 0.89 | BCHE (0.41) | BCHEBACE1HTR1ACHRM2SCN8A | |
| SCHEMBL21632587 | 0.89 | HTR2A (0.33) | BCHEBACE1HTR1AHDAC1 | |
| SCHEMBL21648323 | 0.83 | BCHE (0.40) | BCHEBACE1HTR1ACHRM2SCN8A | |
| Hydrochloric Acid SCHEMBL29692596 | 0.82 | BCHE (0.39) | BCHEBACE1HTR1ACHRM2SCN8A | |
| SCHEMBL21632659 | 0.82 | BCHE (0.35) | BCHEBACE1 | |
| SCHEMBL21648453 | 0.79 | BCHE (0.37) | BCHEBACE1HTR1ACHRM2SCN8A | |
| SCHEMBL24720504 | 0.78 | HTR1A (0.38) | BCHEBACE1HTR1ACHRM2SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606344-B1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | CURZA GLOBAL, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL, LLC (US) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | SRM, PARG, PARN | BCHE 1877/4885BACE1 2824/4885HTR1A 3092/4885 |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | SRM, PARG, PARN | BCHE 1877/4885BACE1 2824/4885HTR1A 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.