Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29692538 | 0.99 | HRH4 (0.50) | HRH4HRH3ALDH1A1CYP3A4TSHR | |
| SCHEMBL21648322 | 0.91 | HRH4 (0.50) | HRH4HRH3ALDH1A1SMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL29692770 | 0.90 | HRH4 (0.49) | HRH4HRH3ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL21632586 | 0.85 | ALDH1A1 (0.39) | HRH4HRH3ALDH1A1CYP3A4TSHR | |
| SCHEMBL21648306 | 0.82 | HRH4 (0.49) | HRH4HRH3ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL21648276 | 0.82 | HRH4 (0.73) | HRH4HRH3SMN1; SMN2CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL29692563 | 0.81 | HRH4 (0.48) | HRH4HRH3ALDH1A1SMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL29885842 | 0.80 | HRH4 (0.71) | HRH4HRH3SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL21648277 | 0.80 | HRH4 (0.49) | HRH4HRH3ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL4917701 | 0.80 | ALDH1A1 (0.56) | HRH4HRH3ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606344-B1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | CURZA GLOBAL, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL, LLC (US) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | SRM, PARG, PARN | HRH4 2152/4885HRH3 618/4885ALDH1A1 2854/4885 |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | SRM, PARG, PARN | HRH4 2152/4885HRH3 618/4885ALDH1A1 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.