Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302214 | 0.83 | SMN1; SMN2 (0.42) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL16093539 | 0.83 | CA12 (0.39) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL21648614 | 0.83 | CASP3 (0.35) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL17399559 | 0.82 | MEN1 (0.35) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9976333 | 0.82 | SMN1; SMN2 (0.34) | MAPTNPC1MEN1KMT2ARAB9A | |
| SCHEMBL21648585 | 0.81 | CA12 (0.34) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL21648613 | 0.81 | CA12 (0.36) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13234516 | 0.80 | MAOB (0.41) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL12452198 | 0.79 | MAPT (0.34) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL17399555 | 0.79 | PDK2 (0.35) | MAPTNPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020019289-A1 | NOVEL RHODAMINE DYE AND APPLICATION THEREOF AGAINST PATHOGENIC BACTERIA | 华东理工大学 | 2020-01-30 | — | — | WO | disclosed |