Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 9/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22640969 | 0.89 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2DGKA | |
| SCHEMBL26049973 | 0.88 | ALDH1A1 (0.35) | KMT2ASMN1; SMN2 | |
| SCHEMBL18768989 | 0.86 | KMT2A (0.33) | KMT2ASMN1; SMN2 | |
| SCHEMBL22272181 | 0.86 | HDAC3 (0.35) | KMT2ASMN1; SMN2 | |
| SCHEMBL20144614 | 0.85 | EPHX2 (0.38) | KMT2ASMN1; SMN2PRKCA | |
| SCHEMBL18867375 | 0.84 | KMT2A (0.32) | KMT2ASMN1; SMN2 | |
| SCHEMBL18573305 | 0.82 | CHRM2 (0.36) | KMT2A | |
| SCHEMBL18782758 | 0.81 | PSMB8 (0.31) | — | |
| SCHEMBL21116928 | 0.81 | TSHR (0.41) | KMT2ASMN1; SMN2LMNA | |
| SCHEMBL22096167 | 0.81 | PRKCA (0.33) | NAAASMN1; SMN2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020020365-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE ELIGLUSTAT | 中国医学科学院药物研究所 | 2020-01-30 | — | — | WO | disclosed |