Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.50 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12839912 | 0.85 | TPSAB1 (0.52) | CA1CA2TPSAB1PRSS1TPSD1 | |
| SCHEMBL26847172 | 0.83 | NPC1 (0.46) | TPSAB1PRSS1TPSD1TPSG1NPC1 | |
| SCHEMBL18617727 | 0.82 | CA1 (0.59) | CA1CA2CA12CA7GAA | |
| SCHEMBL14679398 | 0.81 | CA1 (0.64) | CA1CA2NPC1CA12CA7 | |
| SCHEMBL18617459 | 0.81 | CA1 (0.64) | CA1CA2TPSAB1PRSS1TPSD1 | |
| SCHEMBL23567648 | 0.80 | CA1 (0.54) | CA1CA2NPC1GAAMEN1 | |
| SCHEMBL17282175 | 0.80 | CYP3A4 (0.62) | TPSAB1ALDH1A1HPGD | |
| SCHEMBL30832014 | 0.79 | NAMPT (0.48) | NPC1GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL19734631 | 0.79 | KMT2A (0.59) | CA1CA2CA12CA7GAA | |
| SCHEMBL12765264 | 0.79 | GAA (0.61) | CA1CA2GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023782-A1 | BIFUNCTIONAL COMPOUNDS AS CDK MODULATORS | BIOTHERYX, INC. (US) | 2020-01-30 | — | — | WO | disclosed |