Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075472 | 0.83 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15032273 | 0.82 | NPC1 (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19734631 | 0.81 | KMT2A (0.59) | ALDH1A1KMT2ASMN1; SMN2RAB9AHDAC1 | |
| SCHEMBL15267476 | 0.81 | LOXL2 (0.56) | NAMPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14543244 | 0.79 | SMN1; SMN2 (0.70) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL21648725 | 0.79 | CA1 (0.59) | NAMPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL26847172 | 0.79 | NPC1 (0.46) | NAMPTALDH1A1NPC1L3MBTL1HPGD | |
| SCHEMBL7950040 | 0.78 | RAB9A (0.60) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL969258 | 0.77 | SMN1; SMN2 (0.67) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4424117 | 0.76 | KMT2A (0.68) | NAMPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |