Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21487778 | 0.84 | CYP3A4 (0.36) | TSHRCYP3A4TDP1ALOX15ALOX12 | |
| SCHEMBL410370 | 0.80 | ERN1 (0.58) | ALDH1A1KDM4EMAPT | |
| SCHEMBL4599635 | 0.78 | CYP3A4 (0.55) | TSHRCYP3A4TDP1ALOX15ALOX12 | |
| SCHEMBL9807717 | 0.78 | CYP3A4 (0.55) | TSHRCYP3A4TDP1ALOX15ALOX12 | |
| SCHEMBL14074127 | 0.77 | ALOX5 (0.34) | TSHRCYP3A4TDP1ALOX15ALOX12 | |
| SCHEMBL21487585 | 0.77 | GPR35 (0.47) | TDP1ALOX15ALOX12HIF1AHSD17B10 | |
| SCHEMBL9199758 | 0.73 | MCL1 (0.52) | ALOX15ALOX12HSD17B10HPGDMEN1 | |
| SCHEMBL21602738 | 0.72 | SELL (0.48) | TDP1ALOX15ALOX12HSD17B10ALDH1A1 | |
| SCHEMBL338483 | 0.70 | MCL1 (0.34) | ALOX15ALOX12HSD17B10HPGDMEN1 | |
| SCHEMBL10888518 | 0.70 | CA1 (0.52) | CYP3A4ALDH1A1TTRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739269-B2 | Additive and application thereof | DAXIN MATERIALS CORPORATION (TW) | 2023-08-29 | — | — | US | disclosed |
| WO-2020023438-A2 | PROCESS FOR THE PREPARATION OF BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2020-01-30 | — | — | WO | disclosed |