Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811561 | 0.85 | AR (0.58) | AR | |
| SCHEMBL3610929 | 0.84 | AR (0.60) | AR | |
| SCHEMBL20157461 | 0.83 | GHSR (0.44) | AR | |
| SCHEMBL4877618 | 0.82 | AR (0.59) | AR | |
| SCHEMBL21633534 | 0.81 | TLR8 (0.58) | AR | |
| SCHEMBL4880317 | 0.80 | AR (0.64) | AR | |
| SCHEMBL4635321 | 0.78 | AR (0.60) | AR | |
| SCHEMBL4881177 | 0.78 | AR (0.69) | AR | |
| SCHEMBL3601629 | 0.74 | AR (1.00) | AR | |
| SCHEMBL3603871 | 0.74 | AR (0.73) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3826724-B1 | NOVEL PIPERAZINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN LA ROCHE (CH) | 2022-10-05 | — | — | EP | disclosed |
| WO-2020020800-A1 | NOVEL PIPERAZINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-01-30 | — | — | WO | disclosed |