Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21649366 | 0.83 | AR (0.59) | AR | |
| SCHEMBL2460324 | 0.82 | GRM1 (0.45) | GRM1GRM2KDM4EGRM5HTR7 | |
| SCHEMBL2460325 | 0.82 | GRM1 (0.45) | GRM1GRM2KDM4EGRM5HTR7 | |
| SCHEMBL20140116 | 0.82 | GRM1 (0.45) | GRM1GRM2KDM4EGRM5HTR7 | |
| SCHEMBL19665127 | 0.81 | GRM1 (0.47) | GRM1GRM2KDM4EGRM5HTR7 | |
| SCHEMBL5795243 | 0.81 | GRM1 (0.47) | GRM1GRM2KDM4EGRM5HTR7 | |
| SCHEMBL20140205 | 0.81 | GRM1 (0.47) | GRM1GRM2KDM4EGRM5HTR7 | |
| SCHEMBL27679123 | 0.80 | GHSR (0.45) | GHSRKDM4EHTTWEE1ALDH1A1 | |
| SCHEMBL27679122 | 0.80 | GHSR (0.45) | GHSRKDM4EHTTWEE1ALDH1A1 | |
| SCHEMBL20139200 | 0.79 | GRM1 (0.43) | GRM1GRM2KDM4EGRM5HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |