Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 6/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10215042 | 0.80 | ATM (0.42) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL22796893 | 0.79 | ATM (0.42) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL7945978 | 0.79 | ATM (0.42) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL22511873 | 0.79 | ATM (0.42) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL22511867 | 0.79 | ATM (0.42) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL22512115 | 0.79 | ATM (0.42) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL8249263 | 0.78 | MEN1 (0.42) | ATMPIK3CDPIK3CAPIK3CGALDH1A1 | |
| SCHEMBL23205213 | 0.77 | SMN1; SMN2 (0.50) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL28265994 | 0.77 | ATM (0.40) | ATMVHLPIK3CDPIK3CAPIK3CG | |
| SCHEMBL23201647 | 0.75 | ATM (0.69) | ATMVHLPIK3CDPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023851-A1 | BIFUNCTIONAL SUBSTITUED PYRIMIDINES AS MODULATORS OF FAK PROTEOLYSE | YALE UNIVERSITY (US) | 2020-01-30 | — | — | WO | disclosed |