Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23462265 | 0.88 | ATM (0.48) | MEN1KMT2AALDH1A1TSHRHDAC8 | |
| SCHEMBL2018914 | 0.87 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1TSHRHDAC8 | |
| SCHEMBL2744394 | 0.78 | MEN1 (0.48) | MEN1KMT2AALDH1A1TSHRMMP1 | |
| SCHEMBL3763934 | 0.78 | MEN1 (0.48) | MEN1KMT2AALDH1A1TSHRMMP1 | |
| SCHEMBL5123701 | 0.78 | CYP1A2 (0.51) | ALDH1A1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL21649572 | 0.78 | ATM (0.41) | ALDH1A1PIK3CDPIK3CAPIK3CGATM | |
| SCHEMBL8342239 | 0.78 | CYP1A2 (0.51) | ALDH1A1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL5128225 | 0.78 | CYP1A2 (0.51) | ALDH1A1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL1020672 | 0.78 | CYP1A2 (0.51) | ALDH1A1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL3391831 | 0.78 | CYP1A2 (0.51) | ALDH1A1CYP1A2POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015824-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2007-02-08 | — | — | WO | disclosed |