SCHEMBL2165152

SCHEMBL2165152

Cc1ccc(C(C)(C)C)c(O)c1CCc1c(C)ccc(C(C)(C)C)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.50
GABRB2 P47870 1/20 0.50
CA2 P00918 3/20 0.46
SMN1; SMN2 Q16637 5/20 0.42
CYP2C9 P11712 5/20 0.42
CYP2C19 P33261 4/20 0.42
HIF1A Q16665 4/20 0.42
TP53 P04637 2/20 0.42
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 6/20 0.40
TYR P14679 2/20 0.40
POLB P06746 1/20 0.40
TSHR P16473 3/20 0.37
ALOX15 P16050 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
HSPA5 P11021 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
CA1 P00915 1/20 0.37
HSD17B10 Q99714 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29836467 0.94 GABRA1 (0.48) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL30402247 0.94 GABRA1 (0.48) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL30438452 0.92 GABRA1 (0.47) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL8989595 0.92 GABRA1 (0.47) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL29650379 0.88 CYP2C19 (0.50) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL753473 0.88 CYP2C19 (0.50) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL23941079 0.86 GABRA1 (0.48) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL10245825 0.86 GABRA1 (0.48) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL15450309 0.84 GABRA1 (0.47) GABRA1GABRB2CA2SMN1; SMN2CYP2C9
SCHEMBL9201480 0.81 GABRA1 (0.44) GABRA1GABRB2CA2SMN1; SMN2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7267914-B2 Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2007-09-11 US claimed
US-20110183243-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND ELECTROPHOTOGRAPHIC IMAGING APPARATUS INCLUDING THE PHOTORECEPTOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-07-28 US disclosed
US-7560207-B2 Organic photoreceptor and electrophotographic image forming apparatus including the photoreceptor SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-07-14 US disclosed
US-20080199793-A1 Electrophotographic photoreceptor having excellent electrical properties and image quality and their high stabilities and electrophotographic imaging apparatus employing the same SAMSUNG ELECTRONICS CO., LTD 2008-08-21 US disclosed
US-20080160439-A1 Electrophotographic photoreceptor, method of preparation, and electrophotographic imaging apparatus SAMSUNG ELECTRONICS CO., LTD. 2008-07-03 US disclosed
US-7348115-B2 Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2008-03-25 US disclosed
US-20080014519-A1 Organic photoreceptor and electrophotographic image forming apparatus including the photoreptor SAMSUNG ELECTRONICS CO., LTD. 2008-01-17 US disclosed
US-20080014520-A1 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2008-01-17 US disclosed
EP-1879074-A2 Organic photoreceptor and electrophotographic image forming apparatus including the photoreceptor Samsung Electronics Co., Ltd. (KR) 2008-01-16 EP disclosed
EP-1879073-A2 Organic photoreceptor and electrophotographic image forming apparatus including the organic photoreceptor Samsung Electronics Co., Ltd. (KR) 2008-01-16 EP disclosed
EP-1879076-A2 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor Samsung Electronics Co., Ltd. (KR) 2008-01-16 EP disclosed
US-7267914-B2 Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2007-09-11 US disclosed
US-20070026327-A1 Electrophotographic photoreceptor for preventing image deterioration from repeated use and electrophotographic image forming apparatus employing the photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2007-02-01 US disclosed
US-20050170271-A1 Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method YAMANAMI HIROFUMI (JP) 2005-08-04 US disclosed
US-20030232265-A1 Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2003-12-18 US disclosed
US-5670284-A HAVING CHARGE GENERATING LAYER COMPRISING POLYALKYLENE GLYCOL AND/OR ESTER OR ETHER THEREOF AND/OR CROWN ETHER, CHARGE TRANSPORT LAYER COMPRISING ANTIOXIDANT RICOH COMPANY, LTD. (JP) 1997-09-23 US disclosed