Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19828710 | 0.84 | GAA (0.34) | GABRA1GABRB2ALDH1A1GAAKDM4E | |
| SCHEMBL9754486 | 0.84 | GABRA1 (0.43) | GABRA1GABRB2CA2CYP2C9CYP2C19 | |
| SCHEMBL8316943 | 0.83 | GABRA1 (0.39) | GABRA1GABRB2ALDH1A1POLBGAA | |
| SCHEMBL11495679 | 0.82 | GABRA1 (0.42) | GABRA1GABRB2CA2CYP2C9CYP2C19 | |
| SCHEMBL29650379 | 0.81 | CYP2C19 (0.50) | GABRA1GABRB2CA2CYP2C9CYP2C19 | |
| SCHEMBL2165152 | 0.81 | GABRA1 (0.50) | GABRA1GABRB2CA2CYP2C9CYP2C19 | |
| SCHEMBL753473 | 0.81 | CYP2C19 (0.50) | GABRA1GABRB2CA2CYP2C9CYP2C19 | |
| SCHEMBL23941079 | 0.79 | GABRA1 (0.48) | GABRA1GABRB2CA2CYP2C9CYP2C19 | |
| SCHEMBL30402247 | 0.79 | GABRA1 (0.48) | GABRA1GABRB2CA2CYP2C9CYP2C19 | |
| SCHEMBL29836467 | 0.79 | GABRA1 (0.48) | GABRA1GABRB2CA2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7109269-A | — | — | None | — | — | JP | disclosed |
| JP-H07109269-A | PRODUCTION OF CHROMANE DERIVATIVE AND INTERMEDIATE THEREOF | NIPPON KAYAKU CO LTD | 1995-04-25 | — | — | JP | disclosed |