SCHEMBL216528

SCHEMBL216528

[CH2]Cc1ccc(O)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1803971 0.83 ESR1 (0.32)
SCHEMBL503866 0.77 ESR1 (0.68)
SCHEMBL3076928 0.75
SCHEMBL2686386 0.75 TSHR (0.50)
Hydroquinone SCHEMBL8680894 0.75
SCHEMBL28922458 0.75 IDO1 (0.62)
SCHEMBL36454 0.73 ESR1 (1.00)
SCHEMBL2969737 0.73 ESR1 (1.00)
SCHEMBL3873458 0.73 ESR1 (1.00)
SCHEMBL69344 0.73 ESR1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2344 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4234609-B1 METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS POLYPLUS TRANSFECTION (FR) 2024-07-17 EP claimed
US-20240180932-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS NESTLE SA (CH) 2024-06-06 US claimed
EP-3508202-B1 THERAPEUTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS AND COMPOSITION FOR TREATMENT UNIV KEIO (JP) 2024-02-21 EP claimed
CN-114901316-B Composition for transfecting nucleic acid molecules into cells comprising triazole compounds grafted onto cationic polymers and uses thereof 宝利普拉斯生物转染公司 2024-02-13 CN claimed
EP-4313017-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS Société des Produits Nestlé S.A. (CH) 2024-02-07 EP claimed
US-20230414638-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF NESTLE SA (CH) 2023-12-28 US claimed
WO-2023213715-A1 AMPK ACTIVATOR (CBDA) AND SGLT2 INHIBITOR FOR METABOLIC HEALTH Société des Produits Nestlé S.A. (CH) 2023-11-09 WO claimed
CN-116981452-A Substituted resorcinol compounds for the management of aging and related disorders 雀巢产品有限公司 2023-10-31 CN claimed
CN-116761791-A Substituted resorcinol compounds as AMPK activators and uses thereof 雀巢产品有限公司 2023-09-15 CN claimed
EP-4240342-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF Société des Produits Nestlé S.A. (CH) 2023-09-13 EP claimed
EP-0175525-A1 7-[2-(Dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones SMITHKLINE BEECHAM CORPORATION (US) 1986-03-26 EP claimed
EP-0167288-A2 4-(2-(N,N-disubstituted-amino)ethyl]isatins SMITHKLINE BEECHAM CORPORATION (US) 1986-01-08 EP claimed
US-4554287-A Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones SMITHKLINE BECKMAN CORPORATION (US) 1985-11-19 US claimed
US-4537890-A 2-(3,5-Substituted-2-pyridylalkylamino)-5-oxopyridylmethyl-4-pyrimidones useful as histamine H1 -antagonists SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1985-08-27 US claimed
EP-0125052-A2 Dopaminergic carbostyrils and a process for preparing them SMITHKLINE BECKMAN CORPORATION (US) 1984-11-14 EP claimed
EP-0113964-A1 4-Aminoalkyl-2(3H)-indolones SMITHKLINE BECKMAN CORPORATION (US) 1984-07-25 EP claimed
EP-0031104-A1 Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them SANTEN PHARMACEUTICAL CO., LTD. (JP) 1981-07-01 EP claimed
US-4123607-A BACTERICIDES AMERICAN CYANAMID COMPANY (US) 1978-10-31 US claimed
US-4024156-A Thiophene ethanolamines AMERICAN HOME PRODUCTS CORPORATION (US) 1977-05-17 US claimed
US-4001421-A THIAZOLE CARDIOVASCULAR AGENTS SYNTEX (U.S.A.) INC. (US) 1977-01-04 US claimed