Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2745550 | 0.85 | GFER (0.42) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL4967337 | 0.84 | ESR1 (0.62) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL5536586 | 0.82 | ESR1 (0.59) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL3873458 | 0.82 | ESR1 (1.00) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL69344 | 0.82 | ESR1 (1.00) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL2323477 | 0.80 | ESR1 (0.63) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL504392 | 0.80 | ESR1 (0.63) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL2686704 | 0.80 | ESR1 (0.63) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL3360491 | 0.78 | CA2 (0.59) | ESR1ESR2CA2ALDH1A1KDM4E | |
| SCHEMBL7520034 | 0.78 | TSHR (0.46) | ESR1ESR2CA2ALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116273203-B | Method for preparing cyclohexane fuel by catalytic lignin pyrolysis oil hydrodeoxygenation through hollow NiCo/NC cage-shaped polyhedral catalyst | 宁夏大学 | 2024-07-16 | — | — | CN | claimed |
| WO-2024104384-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | NUCMITO PHARMACEUTICALS CO. LTD. (CN) | 2024-05-23 | — | — | WO | claimed |
| CN-116273203-A | Method for preparing cyclohexane fuel by catalytic lignin pyrolysis oil hydrodeoxygenation through hollow NiCo/NC cage-shaped polyhedral catalyst | 宁夏大学 | 2023-06-23 | — | — | CN | claimed |
| CN-114015082-A | Method for preparing functional grape seed nano-sphere particles by utilizing grape seeds and product thereof | 齐鲁工业大学 | 2022-02-08 | — | — | CN | claimed |
| US-20140275186-A1 | NOVEL NON-STEROIDAL COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | FLX DISCOVERIES OY (FI) | 2014-09-18 | — | — | US | claimed |
| EP-2768814-A1 | NOVEL NON-STEROIDAL COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | FLX Discoveries OY (FI) | 2014-08-27 | — | — | EP | claimed |
| WO-2013057372-A1 | NOVEL NON-STEROIDAL COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | PULKKINEN JUHA (FI) | 2013-04-25 | — | — | WO | claimed |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2013-02-21 | — | — | US | claimed |
| CN-102812033-A | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | INST MATERIA MEDICA CAMS | 2012-12-05 | — | — | CN | claimed |
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | claimed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | claimed |
| CN-1180358-A | Bridged indoles as matrix metalloprotease inhibitors | SYNTEX INC (US) | 1998-04-29 | — | — | CN | claimed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | claimed |
| WO-1997042205-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | claimed |
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | claimed |
| US-5047399-A | Hypotensive Agents | SCHERING CORPORATION (US) | 1991-09-10 | — | — | US | claimed |
| US-5047491-A | Molding materials; waterproofing, oil repellents, antifouling agents | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | claimed |
| EP-0355497-A2 | Polyorganosiloxane compounds | Chisso Corporation (JP) | 1990-02-28 | — | — | EP | claimed |
| US-4537890-A | 2-(3,5-Substituted-2-pyridylalkylamino)-5-oxopyridylmethyl-4-pyrimidones useful as histamine H1 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-08-27 | — | — | US | claimed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275186-A1 | NOVEL NON-STEROIDAL COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, NR5A1, SHBG | ESR1 46/4885ESR2 26/4885CA2 3585/4885 |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | ADORA2A, ADORA3, ADORA1 | ESR1 2260/4885ESR2 3107/4885CA2 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.