Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Paraquat. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.72 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.72 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.72 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.70 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.70 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.70 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.70 |
| ▸ | QDPR | P09417 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paraquat SCHEMBL30968908 | 0.97 | SLC6A4 (0.68) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL599615 | 0.97 | SLC22A2 (0.68) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL6054874 | 0.97 | SLC6A4 (0.68) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL8852265 | 0.97 | SLC22A2 (0.68) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL21652 | 0.96 | SLC6A4 (0.77) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL4895671 | 0.96 | SLC6A4 (0.77) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL11281521 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| SCHEMBL14596518 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL8677067 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL8331549 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 36694 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144260-A1 | COMPOSITION AND METHOD FOR IMPROVING AGRONOMIC TRAITS OF A PLANT | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2026-05-28 | — | — | US | claimed |
| WO-2026104986-A1 | NEW MOLECULES AND THEIR USE IN THE TREATMENT OF PATHOLOGIES RELATED TO OXIDATIVE STRESS | FIDIA FARMACEUTICI S.P.A. (IT) | 2026-05-21 | — | — | WO | claimed |
| CN-122037296-A | MF@NH for detecting paraquat and diquat2Preparation method of Ag SERS sensor | 合肥大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122025715-A | Electrolyte for water-based flow battery and water-based flow battery | 北京工业大学 | 2026-05-12 | — | — | CN | claimed |
| US-12622925-B2 | Edible enterosorbents used to mitigate acute exposures to ingestible environmental toxins following outbreaks, natural disasters and emergencies | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2026-05-12 | — | — | US | claimed |
| WO-2026090486-A1 | ENGINEERED CLOSTRIDIUM CELLS AND METHODS FOR USE THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2026-04-30 | — | — | WO | claimed |
| WO-2026090621-A1 | SYSTEMS, DEVICES, AND METHODS FOR SEPARATION OF METALS FROM WASTE, SCRAP, AND POST-CONSUMER PRODUCTS | SUNCHEM INC. (US) | 2026-04-30 | — | — | WO | claimed |
| EP-4655582-B1 | METHOD FOR DETECTING AND/OR QUANTIFYING, IN A SAMPLE OF BLOOD OR DERIVATE BIOLOGICAL LIQUID, A PANEL OF HAEMATOLOGICAL PARAMETERS | FIDELIO MEDICAL S R L (IT) | 2026-04-29 | — | — | EP | claimed |
| EP-3262179-B1 | ELECTROCHEMICAL BIOREACTOR MODULE AND ENGINEERED METABOLIC PATHWAYS FOR 1- BUTANOL PRODUCTION WITH HIGH CARBON EFFICIENCY | BIOCHEMINSIGHTS INC (US) | 2026-04-29 | — | — | EP | claimed |
| US-12610950-B2 | Method for weed control in lawn or turf | DISCOVERY PURCHASER CORPORATION (US) | 2026-04-28 | — | — | US | claimed |
| EP-0022666-A1 | Pesticide compositions which contain a surface-active agent and method of applying them to plants | Sampson, Michael James (GB) | 1981-01-21 | — | — | EP | claimed |
| EP-0019384-A1 | Pesticidal formulations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-11-26 | — | — | EP | claimed |
| EP-0012525-A1 | Herbicidal compositions containing a herbicidal bipyridylium quaternary salt and an alerting agent | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-06-25 | — | — | EP | claimed |
| US-4203253-A | Process for increasing oleoresin synthesis in pinus species | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1980-05-20 | — | — | US | claimed |
| US-4201566-A | PENETRATING THE TREE WITH A BIPYRIDYLIUM SALT | BROWN CLAUD L | 1980-05-06 | — | — | US | claimed |
| US-4187076-A | Paraquat detection method | THE UNIVERSITY OF MISSISSIPPI (US) | 1980-02-05 | — | — | US | claimed |
| EP-0006293-A1 | Agrochemical formulations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-01-09 | — | — | EP | claimed |
| EP-0004414-A1 | Mixtures of herbicidal pyridyloxyphenoxypropanoic acid derivatives with other herbicides, and processes of killing unwanted plants therewith | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-10-03 | — | — | EP | claimed |
| US-4126468-A | Radiation sensitive compositions of quaternary ammonium salt and carboxylic acid sensitizer | VICKERS LIMITED (GB) | 1978-11-21 | — | — | US | claimed |
| US-4118218-A | HERBICIDES, COATING SOLID DILUENT PARTICLES WITH A BIPYRIDYLIUM DIQUATERNARY SALT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-10-03 | — | — | US | claimed |