Paraquat

Paraquat

SCHEMBL4895671

C[n+]1ccc(-c2cc[n+](C)cc2)cc1.C[n+]1ccc(-c2cc[n+](C)cc2)cc1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.77
SLC22A2 O15244 1/20 0.77
SLC22A1 O15245 1/20 0.77
SLC22A3 O75751 1/20 0.77
PABPC1 P11940 1/20 0.65
APOBEC3A P31941 1/20 0.65
EIF4H Q15056 1/20 0.65
APOBEC3G Q9HC16 1/20 0.65
QDPR P09417 2/20 0.56
HDAC8 Q9BY41 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraquat SCHEMBL21652 1.00 SLC6A4 (0.77) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL4084640 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
SCHEMBL14596518 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL11281521 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL21653 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL8677067 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL9650240 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL8331549 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL22370108 0.96 SLC6A4 (0.72) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
Paraquat SCHEMBL599615 0.93 SLC22A2 (0.68) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 EP disclosed
EP-3645640-B1 SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME DOW SILICONES CORP (US) 2024-03-06 EP disclosed
US-11807775-B2 Silicone-organic copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-11-07 US disclosed
US-11760841-B2 Silicone-polycarbonate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-09-19 US disclosed
EP-3898779-B1 SILICONE-POLYESTER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2023-02-08 EP disclosed
EP-3898781-B1 SILICONE-POLYCARBONATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2023-01-04 EP disclosed
US-20220064482-A1 SILICONE-ORGANIC COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION 2022-03-03 US disclosed
US-20220064383-A1 SILICONE-POLYACRYLATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION 2022-03-03 US disclosed
EP-3645641-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2021-08-11 EP disclosed
EP-3645639-B1 SILICONE-POLYETHER COPOLYMER, ISOCYANATE-FUNCTIONAL SILICONE-POLYETHER COPOLYMER FORMED THEREWITH, SILICONE-POLYETHER-URETHANE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2021-07-21 EP disclosed
US-20140182483-A1 Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts DOW CORNING CORPORATION 2014-07-03 US disclosed
US-20140187783-A1 Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW CORNING CORPORATION 2014-07-03 US disclosed
US-20140183398-A1 Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2014-07-03 US disclosed
US-20140171547-A1 Bismuth Containing Complex and Condensation Reaction Curable Compositions and Methods for the Preparation and Use of the Compositions DOW CORNING CORPORATION 2014-06-19 US disclosed
US-20140135517-A1 Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use DOW CORNING CORPORATION (US) 2014-05-15 US disclosed
US-20140100347-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2014-04-10 US disclosed
US-20140039089-A1 Compositions Containing Phosphonate Catalysts And Methods For The Preparation And Use Of The Compositions DOW CORNING CORPORATION (US) 2014-02-06 US disclosed
US-20140018467-A1 COMPOSITIONS CONTAINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2014-01-16 US disclosed
US-20080118734-A1 Coating Compositions DOW CORNING IRELAND LTD. (IE) 2008-05-22 US disclosed
US-5102446-A Mixture of cacium chloride and ammonium polyphosphate AQUALON COMPANY (US) 1992-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135517-A1 Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use HIRA, HIRIP3, CROCC SLC6A4 4412/4885SLC22A2 4406/4885SLC22A1 4191/4885
US-20140183398-A1 Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts HIRA, ALG8, CAD SLC6A4 4281/4885SLC22A2 3383/4885SLC22A1 3182/4885
US-20140182483-A1 Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts ITGA1, TMT1A, ITGA2 SLC6A4 4173/4885SLC22A2 4190/4885SLC22A1 4070/4885
US-20140187783-A1 Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts HIRA, HACL2, CROCC SLC6A4 4031/4885SLC22A2 4574/4885SLC22A1 4508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.