Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21654322 | 0.74 | MAPK1 (0.31) | MAPK1KMT2A | |
| SCHEMBL21320128 | 0.74 | — | — | |
| SCHEMBL21654043 | 0.72 | MAPT (0.48) | MAPK1KMT2A | |
| SCHEMBL13508330 | 0.71 | PTGS1 (0.46) | MAPK1KMT2A | |
| SCHEMBL20169770 | 0.71 | MAPK1 (0.58) | MAPK1KMT2A | |
| SCHEMBL21654054 | 0.71 | ALDH1A1 (0.47) | MAPK1KMT2APGR | |
| SCHEMBL9823542 | 0.70 | MAPK1 (0.53) | MAPK1KMT2A | |
| SCHEMBL9823473 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL1467949 | 0.70 | — | — | |
| SCHEMBL1680750 | 0.69 | MAPT (0.34) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10993938-B2 | Lactam compound, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-05-04 | — | — | US | disclosed |
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | FURIN, PEPD, PIN1 | MAPK1 4106/4885KMT2A 3643/4885PGR 4721/4885 |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | FURIN, PEPD, PIN1 | MAPK1 4106/4885KMT2A 3643/4885PGR 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.