Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.67 |
| ▸ | CCR5 | P51681 | 1/20 | 0.67 |
| ▸ | CCR8 | P51685 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17051526 | 0.90 | CCR1 (0.52) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL12628202 | 0.88 | CCR1 (0.67) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL17051539 | 0.88 | CCR1 (0.60) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL17051557 | 0.86 | CCR1 (0.58) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL20842553 | 0.85 | CCR1 (0.57) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL14804380 | 0.85 | CCR1 (0.76) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL14804374 | 0.83 | CCR1 (0.73) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL17051563 | 0.82 | CYP3A4 (0.47) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL17055552 | 0.82 | NPC1 (0.50) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL17051506 | 0.82 | CCR1 (0.71) | CCR1CCR5CCR8HDAC6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544365-B2 | Nematic liquid crystal composition | DIC CORPORATION (JP) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544365-B2 | Nematic liquid crystal composition | DOCK5, CDKL5, NCS1 | CCR1 325/4885CCR5 459/4885CCR8 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.