Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620557 | 0.90 | KDM4E (0.40) | RAD51KDM4EGAAALDH1A1GLA | |
| SCHEMBL17620569 | 0.87 | CYP19A1 (0.47) | RAD51KDM4EALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL22449433 | 0.87 | MEN1 (0.49) | RAD51ALDH1A1DHODHMEN1KMT2A | |
| SCHEMBL17620587 | 0.87 | KDM4E (0.49) | KDM4EGAAALDH1A1GLASMN1; SMN2 | |
| SCHEMBL17620578 | 0.87 | TDP1 (0.49) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17620591 | 0.87 | NPC1 (0.44) | RAD51KDM4EGAAALDH1A1GLA | |
| SCHEMBL22449438 | 0.87 | RAD51 (0.50) | RAD51KDM4EGAAALDH1A1GLA | |
| SCHEMBL17620562 | 0.84 | RAB9A (0.40) | RAD51KDM4EGAAALDH1A1GLA | |
| SCHEMBL18396441 | 0.84 | RAD51 (0.53) | RAD51KDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL17620548 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3214085-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | HEESUNG MAT LTD (KR) | 2020-01-29 | — | — | EP | disclosed |