SCHEMBL21656841

SCHEMBL21656841

CCCCc1ccc(Oc2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 2/20 0.64
CYP4F2 P78329 1/20 0.62
PLK1 P53350 1/20 0.55
LPAR1 Q92633 1/20 0.55
LPAR5 Q9H1C0 1/20 0.55
MAPT P10636 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
MDH1 P40925 2/20 0.54
MGLL Q99685 1/20 0.52
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
LOXL2 Q9Y4K0 1/20 0.51
RARB P10826 1/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
CASP1 P29466 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
THRA P10827 1/20 0.50
THRB P10828 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21656840 0.95 CYP4A11 (0.65) CYP4A11CYP4F2LPAR1LPAR5MAPT
SCHEMBL21656842 0.94 CYP4A11 (0.63) CYP4A11CYP4F2LPAR1LPAR5MAPT
SCHEMBL1792416 0.92 CYP4A11 (0.74) CYP4A11CYP4F2PLK1MAPTSMN1; SMN2
SCHEMBL21656469 0.90 CYP4A11 (0.58) CYP4A11CYP4F2PLK1LPAR1LPAR5
SCHEMBL11584932 0.88 MAPT (0.54) CYP4A11PLK1MAPTSMN1; SMN2RARB
SCHEMBL12656086 0.87 RARB (0.68) CYP4A11CYP4F2PLK1MAPTSMN1; SMN2
SCHEMBL8044139 0.87 CYP4A11 (0.75) CYP4A11CYP4F2PLK1MAPTSMN1; SMN2
SCHEMBL1123094 0.87 NPC1 (0.70) CYP4A11CYP4F2PLK1MAPTSMN1; SMN2
SCHEMBL21656942 0.86 ESR1 (0.51) CYP4A11CYP4F2PLK1MAPTSMN1; SMN2
SCHEMBL2354104 0.86 CYP4A11 (0.66) CYP4A11CYP4F2PLK1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK CYP4A11 830/4885CYP4F2 1580/4885PLK1 3032/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK CYP4A11 744/4885CYP4F2 1625/4885PLK1 2623/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK CYP4A11 830/4885CYP4F2 1580/4885PLK1 3032/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR CYP4A11 327/4885CYP4F2 614/4885PLK1 3885/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK CYP4A11 830/4885CYP4F2 1580/4885PLK1 3032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.