Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310466 | 0.90 | TSHR (0.42) | CTSDBACE1TSHRPLA2G4BIDO1 | |
| SCHEMBL20485056 | 0.90 | TSHR (0.42) | TSHRALDH1A1MEN1CYP3A4MAPK1 | |
| SCHEMBL29928740 | 0.89 | ALDH1A1 (0.46) | TSHRALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL20548123 | 0.89 | ALDH1A1 (0.46) | TSHRALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL21169086 | 0.86 | KDM4E (0.39) | TSHRALDH1A1MEN1USP2LMNA | |
| SCHEMBL23267589 | 0.81 | KDM4E (0.37) | CTSDBACE1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8872904 | 0.80 | LTA4H (0.44) | TSHRALDH1A1KDM4E | |
| SCHEMBL16325340 | 0.80 | CYP4F2 (0.37) | — | |
| SCHEMBL10204837 | 0.79 | IDO1 (0.58) | ALDH1A1LMNAIDO1 | |
| SCHEMBL2970007 | 0.79 | IDO1 (0.59) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023813-A1 | PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION | COCRYSTAL PHARMA, INC. (US) | 2020-01-30 | — | — | WO | disclosed |