Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427154 | 0.90 | TTR (0.46) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL30760702 | 0.89 | SLC37A4 (0.55) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL30760687 | 0.88 | SLC37A4 (0.50) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL11302548 | 0.87 | TTR (0.59) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL15427167 | 0.81 | TTR (0.42) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL8996338 | 0.80 | MEN1 (0.55) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL15427190 | 0.78 | TTR (0.44) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL15427159 | 0.78 | ELANE (0.42) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL16921518 | 0.77 | LIG1 (0.39) | TTRKDM4EMEN1ABCC4USP2 | |
| SCHEMBL16921516 | 0.77 | HIF1A (0.39) | TTRALDH1A1MAPTMAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | TTR 4284/4885KDM4E 1197/4885MEN1 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.