Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC37A4 | O43826 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30760687 | 0.95 | SLC37A4 (0.50) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL21657713 | 0.89 | TTR (0.47) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL30760701 | 0.88 | SLC37A4 (0.58) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL30760707 | 0.84 | SLC37A4 (0.46) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL30760692 | 0.82 | TTR (0.56) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL30760694 | 0.81 | SLC37A4 (0.48) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL15427190 | 0.81 | TTR (0.44) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL30760689 | 0.79 | SLC37A4 (0.51) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL15427154 | 0.79 | TTR (0.46) | SLC37A4TTRKDM4EMEN1ABCC4 | |
| SCHEMBL8996338 | 0.79 | MEN1 (0.55) | TTRKDM4EMEN1ABCC4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540224-A1 | COMPOUNDS AND METHOD FOR UPREGULATION OF P53 THROUGH INDUCTION OF MDM2 DEGRADATION | Georgia State University Research Foundation, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023250318-A1 | COMPOUNDS AND METHOD FOR UPREGULATION OF P53 THROUGH INDUCTION OF MDM2 DEGRADATION | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-12-28 | — | — | WO | disclosed |