⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479174 | 0.88 | TSHR (0.30) | — | |
| SCHEMBL2481172 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL22686502 | 0.79 | — | — | |
| SCHEMBL15561070 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL7770560 | 0.72 | FDPS (0.32) | — | |
| SCHEMBL28568734 | 0.72 | — | — | |
| SCHEMBL349145 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL28044809 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL1467767 | 0.71 | — | — | |
| Iodide SCHEMBL5092921 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544434-B2 | Process for the preparation of lisdexamfetamine and related derivatives | NORAMCO, INC. (US) | 2020-01-28 | — | — | US | disclosed |