Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17739999 | 0.89 | NAAA (0.48) | SMN1; SMN2NAAALMNAGNAI3GNAO1 | |
| SCHEMBL19703683 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2NAAALMNAGNAI3GNAO1 | |
| SCHEMBL20936573 | 0.88 | SMN1; SMN2 (0.42) | NAMPTSMN1; SMN2NAAATTRIL2 | |
| SCHEMBL23347014 | 0.87 | SMN1; SMN2 (0.43) | NAMPTSMN1; SMN2NAAATTRIL2 | |
| SCHEMBL6849179 | 0.87 | PTGS1 (0.47) | NAMPTSMN1; SMN2NAAATTRIL2 | |
| SCHEMBL19703588 | 0.86 | CNR1 (0.38) | NAMPTSMN1; SMN2NAAATTRIL2 | |
| SCHEMBL19703687 | 0.86 | SMN1; SMN2 (0.38) | NAMPTSMN1; SMN2NAAATTRIL2 | |
| SCHEMBL20936656 | 0.86 | SMN1; SMN2 (0.40) | NAMPTSMN1; SMN2NAAATTRIL2 | |
| SCHEMBL14872066 | 0.86 | NAAA (0.55) | SMN1; SMN2NAAALMNAGNAI3GNAO1 | |
| SCHEMBL2779228 | 0.86 | NAAA (0.55) | SMN1; SMN2NAAALMNAGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199247-A1 | ANTIBODY CONJUGATES OF IMMUNE-MODULATORY COMPOUNDS AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2020-06-25 | — | — | US | disclosed |
| US-20200031798-A1 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | ARS Pharmaceuticals, Inc. | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031798-A1 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | TLR8, TLR3, TLR5 | NAMPT 2331/4885SMN1; SMN2 2986/4885NAAA 552/4885 |
| US-20200199247-A1 | ANTIBODY CONJUGATES OF IMMUNE-MODULATORY COMPOUNDS AND USES THEREOF | LTK, TGFBR2, TNIK | NAMPT 1668/4885SMN1; SMN2 4212/4885NAAA 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.