Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 7/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362405 | 0.85 | TSHR (0.54) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL28366032 | 0.84 | TSHR (0.53) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL31053374 | 0.83 | L3MBTL1 (0.60) | L3MBTL1TDP1TAAR1MEN1KMT2A | |
| SCHEMBL513027 | 0.83 | L3MBTL1 (0.60) | L3MBTL1TDP1TAAR1MEN1KMT2A | |
| SCHEMBL28512693 | 0.83 | TSHR (0.51) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL28366194 | 0.83 | TSHR (0.51) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL8431889 | 0.83 | TSHR (0.51) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL1555236 | 0.82 | ALDH1A1 (0.60) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL14223949 | 0.82 | MCL1 (0.44) | L3MBTL1TDP1FAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL23609638 | 0.81 | TSHR (0.50) | L3MBTL1TDP1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020020097-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | BEIGENE, LTD. (KY) | 2020-01-30 | — | — | WO | disclosed |