Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21659567 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AGAAHSD17B10MMP2 | |
| SCHEMBL24539765 | 0.67 | EPHX1 (0.54) | SMN1; SMN2RAB9AGAAHSD17B10MMP2 | |
| SCHEMBL21659929 | 0.66 | LMNA (0.30) | LMNACYP3A4 | |
| SCHEMBL21786685 | 0.63 | EPHX1 (0.46) | SMN1; SMN2RAB9AGAAHSD17B10MMP2 | |
| SCHEMBL19429723 | 0.62 | EPHX1 (0.44) | SMN1; SMN2RAB9AGAAHSD17B10MMP2 | |
| SCHEMBL5949707 | 0.61 | EPHX1 (0.48) | SMN1; SMN2RAB9AGAANPC1L3MBTL1 | |
| SCHEMBL15800512 | 0.61 | SMN1; SMN2 (0.30) | SMN1; SMN2HSD17B10 | |
| SCHEMBL17301562 | 0.61 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AGAAMAPK1HSD17B10 | |
| SCHEMBL20662511 | 0.60 | CTSV (0.41) | SMN1; SMN2RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL22815254 | 0.60 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9AGAAHSD17B10MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143154-B1 | CHEMICALLY-LOCKED BISPECIFIC ANTIBODIES | SORRENTO THERAPEUTICS INC (US) | 2020-01-29 | — | — | EP | disclosed |