Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.62 |
| ▸ | ADA | P00813 | 10/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21659666 | 1.00 | ADORA2A (0.62) | ADORA2AADAHDAC1 | |
| SCHEMBL21659634 | 1.00 | ADORA2A (0.62) | ADORA2AADAHDAC1 | |
| SCHEMBL23868396 | 0.94 | ADORA2A (0.61) | ADORA2AADAHDAC1 | |
| SCHEMBL21659660 | 0.92 | ADORA2A (0.62) | ADORA2AADAHDAC1 | |
| SCHEMBL21659669 | 0.89 | ADORA2A (0.67) | ADORA2AADAHDAC1 | |
| SCHEMBL21659663 | 0.86 | ADORA2A (0.53) | ADORA2A | |
| SCHEMBL21659702 | 0.86 | ADA (0.65) | ADORA2AADA | |
| SCHEMBL21659691 | 0.82 | ADORA2A (0.61) | ADORA2AADA | |
| SCHEMBL21480052 | 0.82 | ADA (0.66) | ADA | |
| SCHEMBL21659304 | 0.81 | ADORA2A (0.65) | ADORA2AADAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300936-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | BEONE MEDICINES I GMBH (CH) | 2021-09-30 | — | — | US | disclosed |
| WO-2020020097-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | BEIGENE, LTD. (KY) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300936-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | ADORA2A, ADORA3, ADORA2B | ADORA2A 1/4885ADA 412/4885HDAC1 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.