Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19733921 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 | |
| SCHEMBL21342932 | 0.83 | KMT2A (0.57) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 | |
| SCHEMBL9224886 | 0.83 | HPGD (0.46) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9356263 | 0.82 | HRH4 (0.44) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9356271 | 0.82 | HRH4 (0.44) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 | |
| SCHEMBL31258275 | 0.81 | LMNA (0.46) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 | |
| SCHEMBL23518457 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1HRH4 | |
| SCHEMBL7301249 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1HRH4 | |
| SCHEMBL23901605 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 | |
| SCHEMBL24526798 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2AHPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550149-B2 | PPAR agonists and methods of use thereof | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2020-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550149-B2 | PPAR agonists and methods of use thereof | PPARD, PPARG, PPARA | ALDH1A1 1520/4885KMT2A 3234/4885HPGD 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.