SCHEMBL21660509

SCHEMBL21660509

COCc1ccc2c(NS(=O)(=O)c3c(OC)cccc3OC)noc2c1

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.69
KAT6A Q92794 20/20 0.69
KAT6B Q8WYB5 14/20 0.69
KAT5 Q92993 9/20 0.69
KAT8 Q9H7Z6 9/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609033 0.85 KAT6A (0.74) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31605632 0.85 KAT6A (0.74) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21660539 0.83 KAT7 (0.70) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817422 0.82 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609246 0.81 KAT6A (0.64) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31511092 0.79 KAT6A (0.64) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30838425 0.79 KAT7 (0.72) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609077 0.79 KAT7 (0.72) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609082 0.77 KAT6A (0.58) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30545817 0.77 KAT6A (0.63) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT7 490/4885KAT6A 877/4885KAT6B 1005/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT7 490/4885KAT6A 878/4885KAT6B 1007/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B KAT7 271/4885KAT6A 160/4885KAT6B 264/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 KAT7 490/4885KAT6A 878/4885KAT6B 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.