SCHEMBL21660798

SCHEMBL21660798

CCC(C)c1ccc(N(c2ccc(N)cc2)c2ccc(NC(C)(C)C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
NPSR1 Q6W5P4 1/20 0.38
CYP2C9 P11712 3/20 0.37
ALDH1A1 P00352 5/20 0.37
TDP1 Q9NUW8 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
MAPT P10636 3/20 0.37
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 2/20 0.36
USP2 O75604 1/20 0.36
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PSMD14 O00487 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21660875 0.85 GRIA4 (0.42) TSHRNPSR1CYP2C9ALDH1A1MAPT
SCHEMBL18812295 0.84 TSHR (0.50) TSHRNPSR1CYP2C9ALDH1A1TDP1
SCHEMBL8673666 0.81 GRIA4 (0.46) TSHRCYP2C9ALDH1A1TDP1L3MBTL1
SCHEMBL20208303 0.81 TSHR (0.40) TSHRNPSR1CYP2C9ALDH1A1TDP1
SCHEMBL21660583 0.80 ALDH1A1 (0.62) TSHRCYP2C9ALDH1A1TDP1L3MBTL1
SCHEMBL18408674 0.78 TSHR (0.38) TSHRNPSR1CYP2C9ALDH1A1TDP1
SCHEMBL112316 0.77 ALDH1A1 (0.53) TSHRNPSR1CYP2C9ALDH1A1TDP1
SCHEMBL20208302 0.77 TSHR (0.39) TSHRNPSR1CYP2C9ALDH1A1TDP1
Hydrochloric Acid SCHEMBL2863291 0.75 ALDH1A1 (0.52) TSHRNPSR1CYP2C9ALDH1A1MAPT
SCHEMBL2341420 0.75 MAPT (0.42) TSHRCYP2C9ALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020027014-A1 POLYMER AND USE OF SAME 日産化学株式会社 2020-02-06 WO disclosed