⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17773008 | 0.87 | CTSA (0.32) | — | |
| SCHEMBL23743800 | 0.86 | — | — | |
| SCHEMBL19729233 | 0.84 | ALDH1A1 (0.31) | — | |
| SCHEMBL24114232 | 0.80 | PNP (0.33) | — | |
| SCHEMBL19959673 | 0.72 | — | — | |
| SCHEMBL17772918 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL19729243 | 0.72 | CTSA (0.31) | — | |
| SCHEMBL21686973 | 0.71 | KISS1R (0.33) | — | |
| SCHEMBL19737217 | 0.70 | — | — | |
| SCHEMBL24015835 | 0.68 | ACACB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025824-A1 | INJECTABLE SOLUTION AT PH 7, COMPRISING AT LEAST ONE BASAL INSULIN WITH A PI BETWEEN 5.8 AND 8.5, AT LEAST ONE IONIC SPECIES, AND AN AMPHIPHILIC COMPOUND BEARING HYDROPHOBIC RADICALS | ADOCIA (FR) | 2020-02-06 | — | — | WO | disclosed |
| WO-2020025826-A1 | COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AT LEAST ONE IONIC SPECIES AND AN AMPHIPHILIC COMPOUND CONTAINING HYDROPHOBIC RADICALS | ADOCIA (FR) | 2020-02-06 | — | — | WO | disclosed |