Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 10/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015600 | 0.92 | TRPV1 (0.46) | TGFBR1TRPV1ABL1BCRMETAP2 | |
| SCHEMBL19794448 | 0.92 | TRPV1 (0.46) | TGFBR1TRPV1ABL1BCRMETAP2 | |
| SCHEMBL21662243 | 0.90 | TGFBR1 (0.38) | TGFBR1TRPV1KIF11ABL1BCR | |
| SCHEMBL19831193 | 0.89 | TRPV1 (0.40) | TGFBR1TRPV1ABL1BCRMETAP2 | |
| SCHEMBL19831001 | 0.89 | TRPV1 (0.40) | TGFBR1TRPV1ABL1BCRMETAP2 | |
| SCHEMBL23956266 | 0.88 | TGFBR1 (0.52) | TGFBR1SMOASIC3 | |
| SCHEMBL21662273 | 0.88 | TGFBR1 (0.52) | TGFBR1SMOASIC3 | |
| SCHEMBL19794405 | 0.87 | NPC1 (0.40) | TGFBR1TRPV1KIF11ABL1BCR | |
| SCHEMBL21662242 | 0.85 | TRPV1 (0.41) | TGFBR1TRPV1ABL1BCRMETAP2 | |
| SCHEMBL18015581 | 0.85 | TRPV1 (0.41) | TGFBR1TRPV1ABL1BCRMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601257-B1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-20200039903-A1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | PAH, ALG3, DDC | TGFBR1 953/4885TRPV1 359/4885KIF11 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.