Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128853 | 0.93 | HRH3 (0.38) | HRH3MAOBALDH1A1GNAI3GNAO1 | |
| SCHEMBL26972454 | 0.89 | HRH3 (0.41) | HRH3MAOBALDH1A1USP2HPGD | |
| SCHEMBL22560691 | 0.87 | HRH3 (0.41) | HRH3MAOBALDH1A1GNAI3GNAO1 | |
| SCHEMBL20128852 | 0.87 | HRH3 (0.35) | HRH3MAOB | |
| SCHEMBL19958946 | 0.85 | ALDH1A1 (0.36) | HRH3ALDH1A1 | |
| SCHEMBL20128871 | 0.85 | HRH3 (0.33) | HRH3MAOBALDH1A1 | |
| SCHEMBL13801832 | 0.83 | HRH3 (0.54) | HRH3MAOBALDH1A1 | |
| SCHEMBL13174317 | 0.83 | ALDH1A1 (0.47) | HRH3ALDH1A1USP2HPGD | |
| SCHEMBL26972452 | 0.82 | HRH3 (0.40) | HRH3MAOB | |
| SCHEMBL22536255 | 0.82 | HRH3 (0.38) | HRH3MAOBALDH1A1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038513-A1 | MODULATORS OF FAK PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038513-A1 | MODULATORS OF FAK PROTEOLYSIS AND ASSOCIATED METHODS OF USE | PTK2, CTTN, CRBN | HRH3 3687/4885MAOB 1252/4885ALDH1A1 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.