SCHEMBL2166602

SCHEMBL2166602

O=C1C=C(Br)/C(=C\Br)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1960492 1.00
SCHEMBL1960493 1.00
SCHEMBL12402358 0.79
SCHEMBL4651396 0.74
SCHEMBL4651394 0.74
SCHEMBL6600467 0.74
SCHEMBL16628829 0.71 ALDH1A1 (0.50)
SCHEMBL16628828 0.71 ALDH1A1 (0.50)
SCHEMBL3200760 0.69
SCHEMBL3200990 0.69 BACE1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024144052-A1 DENTAL IMPLANT HAVING EXCELLENT INTERNAL ANTIBACTERIAL PROPERTIES 오스템임플란트 주식회사 2024-07-04 WO disclosed
US-11964935-B2 Gingerol derivative having inhibitory activity against biofilm formation and pharmaceutical composition comprising same as effective ingredient for preventing or treating biofilm-caused infection symptom KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2024-04-23 US disclosed
EP-3917909-A1 DISULPHIDE COMPOUNDS Neem Biotech Limited (GB) 2021-12-08 EP disclosed
US-10908151-B2 Compositions and methods for cancer diagnosis MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-02-02 US disclosed
US-20200283364-A1 GINGEROL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST BIOFILM FORMATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING BIOFILM-CAUSED INFECTION SYMPTOM KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2020-09-10 US disclosed
WO-2020157463-A1 DISULPHIDE COMPOUNDS NEEM BIOTECH LIMITED (GB) 2020-08-06 WO disclosed
US-20190250152-A1 COMPOSITIONS AND METHODS FOR CANCER DIAGNOSIS BHATIA, SANGEETA N. 2019-08-15 US disclosed
US-10234449-B2 Compositions and methods for cancer diagnosis MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-03-19 US disclosed
US-20160033485-A1 COMPOSITIONS AND METHODS FOR CANCER DIAGNOSIS BHATIA, SANGEETA N. 2016-02-04 US disclosed
EP-2350036-B1 METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS PIERRE FABRE DERMO COSMÉTIQUE (FR) 2015-04-15 EP disclosed
WO-2014146035-A2 COMPOSITIONS AND METHODS FOR CANCER DIAGNOSIS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-09-18 WO disclosed
WO-2014071457-A1 DUAL ACTION NITRIC OXIDE DONORS AND THEIR USE AS ANTIMICROBIAL AGENTS NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2014-05-15 WO disclosed
US-8586618-B2 Furanone compounds and lactam analogues thereof BIOSIGNAL LIMITED (AU) 2013-11-19 US disclosed
US-8563548-B2 Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions PIERRE FABRE DERMO-COSMETIQUE (FR) 2013-10-22 US disclosed
EP-2350036-A1 METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS Pierre Fabre Dermo-Cosmétique (FR) 2011-08-03 EP disclosed
US-20110184059-A1 METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS PIERRE FABRE DERMO-COSMETIQUE (FR) 2011-07-28 US disclosed
WO-2010034827-A1 METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS PIERRE FABRE DERMO-COSMETIQUE (FR) 2010-04-01 WO disclosed
US-20100035948-A1 Furanone compounds and lactam analogues thereof UNILEVER PLC (GB) 2010-02-11 US disclosed
WO-2008040097-A1 FURANONE COMPOUNDS AND LACTAM ANALOGUES THEREOF BIOSIGNAL LIMITED (AU) 2008-04-10 WO disclosed