SCHEMBL21666748

SCHEMBL21666748

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4cccc5oc6c(-n7c8ccccc8c8cc(-c9ccccc9)ccc87)cccc6c45)n3)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
PLA2G2A P14555 3/20 0.31
PLA2G4A P47712 3/20 0.31
PLA2G10 O15496 1/20 0.31
TSPO P30536 1/20 0.31
MAPT P10636 3/20 0.30
PRKDC P78527 1/20 0.30
ALOX5 P09917 1/20 0.30
KDM4E B2RXH2 2/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALDH1A1 P00352 2/20 0.30
HPGD P15428 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21667082 0.98 PIM1 (0.33) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL21667028 0.98 PIM1 (0.33) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL21671095 0.98 PIM1 (0.33) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL21667071 0.98 PIM1 (0.33) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL25117351 0.97 TSHR (0.33) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL21666751 0.96 PIM1 (0.31) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL21898466 0.96 PIM1 (0.34) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL25954484 0.96 PIM1 (0.34) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL21666956 0.96 TSHR (0.34) TSHRPIM1CSNK2A2CSNK2BPIM3
SCHEMBL21898588 0.96 TSHR (0.34) TSHRPIM1CSNK2A2CSNK2BPIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257586-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-10-11 EP disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-11527723-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-12-13 US disclosed
EP-3604298-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO LTD (KR) 2022-03-30 EP disclosed
WO-2022025714-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2022-02-03 WO disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 WO disclosed
EP-3604296-B1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT LT MATERIALS CO LTD (KR) 2021-07-28 EP disclosed
US-20210057651-A1 ORGANIC LIGHT EMITTING DEVICE, METHOD FOR MANUFACTURING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2021-02-25 US disclosed
US-20200123133-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME HEESUNG MATERIAL LTD. (KR) 2020-04-23 US disclosed
EP-3604296-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT Heesung Material Ltd. (KR) 2020-02-05 EP disclosed
EP-3604298-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME Heesung Material Ltd. (KR) 2020-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200123133-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 TSHR 4080/4885PIM1 1259/4885CSNK2A2 958/4885
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 TSHR 4694/4885PIM1 3702/4885CSNK2A2 963/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 TSHR 4296/4885PIM1 2458/4885CSNK2A2 569/4885
US-11527723-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 TSHR 4080/4885PIM1 1259/4885CSNK2A2 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.