Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21667352 | 0.73 | KMT2A (0.41) | CYP3A4CYP2B6 | |
| SCHEMBL21667390 | 0.73 | POLB (0.39) | — | |
| SCHEMBL16321589 | 0.67 | KMT2A (0.41) | CYP3A4CYP2B6 | |
| SCHEMBL16321588 | 0.67 | KMT2A (0.41) | CYP3A4CYP2B6 | |
| SCHEMBL9218487 | 0.66 | SMN1; SMN2 (0.39) | CYP3A4CYP2B6 | |
| SCHEMBL24313029 | 0.65 | CYP3A4 (0.48) | CYP3A4CYP2B6 | |
| SCHEMBL16356126 | 0.65 | CYP3A4 (0.76) | CYP3A4CYP2B6 | |
| SCHEMBL30825575 | 0.64 | SMN1; SMN2 (0.38) | CYP3A4CYP2B6 | |
| SCHEMBL21667210 | 0.64 | SMN1; SMN2 (0.47) | CYP3A4CYP2B6 | |
| SCHEMBL21667361 | 0.64 | SMN1; SMN2 (0.49) | CYP3A4CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010910-B1 | PYRIMIDINEDIONE COMPOUNDS AGAINST CARDIAC CONDITIONS | MYOKARDIA INC (US) | 2020-02-05 | — | — | EP | disclosed |