Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935282 | 0.86 | ALDH1A1 (0.54) | BACE1ALDH1A1L3MBTL1ELANEMAOB | |
| SCHEMBL4623521 | 0.80 | CYP1A2 (0.54) | ALDH1A1MAPTKDM4ETDP1HPGD | |
| SCHEMBL4623519 | 0.80 | CYP1A2 (0.54) | ALDH1A1MAPTKDM4ETDP1HPGD | |
| SCHEMBL28322152 | 0.79 | BACE1 (0.54) | BACE1ALDH1A1MAOBMAPTKDM4E | |
| SCHEMBL9822773 | 0.78 | BACE1 (0.44) | BACE1ALDH1A1MAOBLMNAMAPT | |
| SCHEMBL14895292 | 0.78 | KDM4E (0.39) | BACE1ALDH1A1ELANECDK4CCND1 | |
| SCHEMBL11749724 | 0.78 | MEN1 (0.43) | BACE1ALDH1A1L3MBTL1ELANELMNA | |
| SCHEMBL6262373 | 0.74 | ALDH1A1 (0.51) | BACE1ALDH1A1L3MBTL1MAOBPSMB5 | |
| SCHEMBL28398139 | 0.74 | CDK4 (0.65) | ALDH1A1L3MBTL1CDK4CCND1CCNB2 | |
| SCHEMBL9063138 | 0.74 | CDK4 (0.65) | ALDH1A1L3MBTL1CDK4CCND1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028757-A1 | LATE SV40 FACTOR (LSF) INHIBITORS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-02-06 | — | — | WO | disclosed |