Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12869658 | 0.81 | MAPT (0.48) | BACE1KDM4EKMT2ASMN1; SMN2HDAC8 | |
| SCHEMBL21667412 | 0.79 | BACE1 (0.41) | BACE1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL953704 | 0.78 | CYP1A1 (0.56) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL953703 | 0.78 | CYP1A1 (0.56) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL3212560 | 0.78 | BACE1 (0.81) | BACE1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL3212534 | 0.78 | BACE1 (0.81) | BACE1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL19244301 | 0.77 | LMNA (0.60) | KDM4EKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6388238 | 0.77 | LMNA (0.60) | KDM4EKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10935282 | 0.77 | ALDH1A1 (0.54) | BACE1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12190688 | 0.77 | TYR (0.46) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305024-B | Synthetic method of Beloraib intermediate | 鲁南制药集团股份有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-110305024-B | Synthetic method of Beloraib intermediate | 鲁南制药集团股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-110305024-A | A kind of synthetic method of Beloranib intermediate | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | disclosed |