Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456037 | 0.85 | ALDH1A1 (0.36) | HPGDTSHRSMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL7946977 | 0.83 | HPGD (0.49) | HPGDTSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL12806459 | 0.80 | LPAR1 (0.49) | TSHRLMNAGAALPAR1KDM4E | |
| SCHEMBL30626962 | 0.80 | LPAR1 (0.49) | TSHRLMNAGAALPAR1KDM4E | |
| SCHEMBL31096231 | 0.79 | TSHR (0.56) | HPGDTSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL182753 | 0.79 | TSHR (0.56) | HPGDTSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL20563947 | 0.79 | TSHR (0.42) | HPGDTSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL9946005 | 0.78 | KDM4E (0.50) | HPGDTSHRKMT2AHTTRECQL | |
| SCHEMBL8246277 | 0.78 | ALDH1A1 (0.55) | HPGDTSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL10435972 | 0.78 | GABRA1 (0.42) | HPGDTSHRLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028757-A1 | LATE SV40 FACTOR (LSF) INHIBITORS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-02-06 | — | — | WO | disclosed |