Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14479290 | 0.82 | NPC1 (0.40) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24749936 | 0.81 | NFE2L2 (0.39) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10073404 | 0.80 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21649876 | 0.78 | TRPA1 (0.39) | NFE2L2RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL11410251 | 0.77 | SIRT2 (0.43) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11410253 | 0.77 | SIRT2 (0.43) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7542298 | 0.74 | NFE2L2 (0.41) | NFE2L2ERN1GAAACHEALDH1A1 | |
| SCHEMBL29956284 | 0.74 | ERN1 (0.57) | NFE2L2ERN1ACHELMNAALDH1A1 | |
| SCHEMBL97029 | 0.74 | ERN1 (0.57) | NFE2L2ERN1ACHELMNAALDH1A1 | |
| SCHEMBL16951325 | 0.74 | ERN1 (0.42) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |